SERUM UREA TEST

Is an indicator of renal function but is more affected by state of hydration and dietary intake. CREATININE is therefore more preferred.

What are normal ranges for UREA TEST?

Adults: 3.3–7.7 mmol/l OR 20–46 mg/100 ml

Infants: 1.3–5.8 mmol/l OR 8–35 mg/100 ml

Values are higher in the elderly and slightly lower in females.

What causes rise in serum Urea levels?

Renal causes of increase are same as those of CREATININE
Non-renal causes: Slight increases in urea (not more than three times the upper limit of the reference range) may occur when there is:
– Dehydration
– Diuretic therapy
– Gastrointestinal blood loss
Any condition associated with increased protein breakdown such as pneumonia, malaria, meningitis, typhoid, major trauma, and surgical operations.

What causes low serum levels?

Low urea levels may be found in:
– Pregnancy
– Malnutrition and AIDS
– Severe liver disease
– Water overload