SEROLOGY TESTS PART 2

Antistreptolysin O Test (ASOT)

This test is used to detect the presence of Antistreptolysin O (ASO) antibodies in the serum. It widely used to detect conditions resulting from streptococcal infection and conditions secondary to a streptococcal infection. It also assists in the diagnosis of rheumatic fever, glomerulonephritis, bacterial endocarditis and scarlet fever.

C-Reactive Protein

The protein rises during inflammation and tissue destruction. It thus tested to chart to he progress of Rheumatoid arthritis, acute rheumatic fever, widespread malignancy and bacterial infections.

Cold Agglutinins

This detects presence of antibodies called cold Agglutinins. It is performed by incubating the patient’s serum with erythrocytes as cold temperature. The agglutination confirms the presence of as antibodies. It used to diagnose Infectious mononucleosis, mycoplasma pneumonia, chronic parasitic infections and lymphoma.

ABO and Rh typing

It is done to prevent transfusion and transplant reactions and to identify problems such as hemolytic diseases of the Newborn.

Rh antibody Titre

Detects amounts of antibodies in the blood. The antibodies can occur in a pregnant woman who is Rh-negative and is carrying an Rh-positive foetus. Most frequently applied in detection of Rh incompatibility problem with a mother and her unborn child.

See also:

Serology tests part 1

SEROLOGY TESTS PART 1

Hepatitis Tests

It is performed to viral hepatitis and the type of hepatitis present e.g A, B, C & D

Syphilis Tests

The method used is Venereal Disease Research Laboratories (VDRL) and the rapid plasma reagin (RPR) test. The test results are reported as none-reactive, weakly reactive or reactive. Weakly reactive results are considered positive for to the presence of syphilis antibodies. This is a screening test thus a more specific testing for final diagnosis Incase of positive result.

Mono Test

It is used to detect the infectious mononucleosis via identification of heterophile antibody.

Rheumatoid Factor

Rheumatoid arthritis is a chronic inflammatory disease that affects the joints of the body. Rheumatoid factor is antibody produced in this condition hence is tested for diagnosis.

See also:

Serology test part 2