Occurs when platelet count rises above the normal range of 150–400 10^9 per litre of blood
What causes Thrombocytosis
● Chronic myeloproliferative diseases, e.g. essential thrombocythemia, polycythaemia vera, chronic myeloid leukaemia, myelofibrosis.
● Carcinoma (disseminated)
● Chronic inflammatory disease, e.g. tuberculosis
● Haemorrhage
● Sickle cell disease associated with a nonfunctioning spleen or after splenectomy.
● Iron deficiency anaemia, associated with active bleeding.
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